抄録
The small intestinal transplantation is considered to be the radical operation for short bowel syndrome in pediatric patients. Because the small intestine contains an extensive number of immunologically competent cells, the most complex and difficult problems to overcome have been the immunologic responses by the host and graft following small-intestinal transplantation. The use of different inbred strains allows experimental designs for special immunological questions. We have examined two kinds of procedures for graft harvesting and compared each other. One is the graft harvesting with the short vascular pedicle (Group I, n = 90) , and the other is that with long vascular pedicle (Group II, n = 106) . In spite of taking the longer time for harvesting the graft, the technical success rate of recipient operation was significantly higher in Group II than that in Group I. The precise technique of Group II was described in this paper. The main technical failures of Group I were thrombus, congestion, and hypoperfusion, while, that of Group II was hemorrhage. In the course of graft harvesting, one of the most important points was to keep the sufficient blood flow of the graft by ligating the distal abdominal aorta, renal arteries, and the celiac artery in the early stage of the operation.
