気管支喘息に対する PEEP の効果

抄録

The use of positive end-expiratory pressure (PEEP) in acute bronchial asthma has traditionally discouraged, because PEEP may produce distension of the lung and barotrauma. We reports its use in 10 month-old baby who got status asthmaticus after being induced anesthesia with oxygen and sevoflurane. Ausculation revealed wheezing and airway pressure was increased. When PEEP of 5 cmH_2O was applied, the ausculation revealed no wheezing, and on flow-volume curve, expiratory tidal volume and early expiratory flow were increased, the time constant was decreased. This observation suggests that PEEP may produce the improvement of functional airway obstruction, the reduction of airway resistance, and the increase of expiratory flow volume in acute bronchial asthma.