Blood & Vessel
Online ISSN : 1884-2372
Print ISSN : 0386-9717
Plasminogen activator in tracheobronchial secretion of rat
Effect of some vasoactive drugs to its activity
Tadayoshi KOSUGIOsamu MATSUOHisashi MIHARAKenji AKAZAWA
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1980 Volume 11 Issue 1 Pages 98-101

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Abstract
In order to clarify the mechanism of the release of the plasminogen activator (Plg. Act.) in the tracheobronchial secretion of rat, the effect of some vasoactive drugs to this activity in the secretion was studied in this experiment.
The results obtained from this experiment were as follows: It was observed that after the injection of noradrenalin the blood pressure was temporarily elevated and the fibrinolytic activity was too elevated. Following these changes the activity of Plg. Act. in the secretion was increased in comparison with the injection of atropine sulfate.
From these results it was suggested that the release of Plg. Act. into the respiratory lumen might be partly regulated by neurogenic system.
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© The Japanese Society on Thrombosis and Hemostasis
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