Abstract
In order to clarify the mechanism of the release of the plasminogen activator (Plg. Act.) in the tracheobronchial secretion of rat, the effect of some vasoactive drugs to this activity in the secretion was studied in this experiment.
The results obtained from this experiment were as follows: It was observed that after the injection of noradrenalin the blood pressure was temporarily elevated and the fibrinolytic activity was too elevated. Following these changes the activity of Plg. Act. in the secretion was increased in comparison with the injection of atropine sulfate.
From these results it was suggested that the release of Plg. Act. into the respiratory lumen might be partly regulated by neurogenic system.