抄録
It has been reported that many parameters relating to hemostasi, coagulation and fibrinolysis vary by amounts of exercise given.
We studied effects on platelet aggregation of abrupt physical exercises given to healthy individuals. A total of twenty healthy adults, 11 males and 9 females (ages 19-33, average 24.7) were subjected 2.6 kilometers of exercise jog and walk, and we determined their platelet counts in peripheral blood, amounts of plasma cetecholamines, apolipoproteins, β-thromboglobulin (β-TG) and thromboxane B2 (TxB2). The values before and after the exercise were compared, where platelet counts showed an increase (p<0.01), and cate-cholomines (p<0.01), apolipoproteines (p<0.05) and β-TG (p<0.01) revealed a rise in their blood concertrations. On the contrary, TxB2 tend to decrease after the exercise. Exercise-induced change in platelet aggregability was variable. Furthermore, concertrations of β-TG and TxB2 in platelet rich plasma (PRP) stimulated with a low concentration of collagen (0.5μg/ml) increased after the exercise.
Accordingly, abrupt exercises given to healthy individuals cause no marked platelet activation in vivo, but they make platelets more susceptible to activating agents in vitro.
