大動脈減圧反射による循環血液量の変化の検討

とくに代用血漿使用後の変化について

抄録

The variation of blood pressure after injecting 2ml/kg of body weight of blood rapidly into the aorta was recorded by electromanometer experimentally using mongrel dogs.
The curves were biphasic, and the ratios of the height of initial rise and the depth of late drop to the pulse pressure were calculated, and normal ranges were set separately.
Those ranges are valid over three hours' experiment in anesthetic condition.
After replacement of 20ml/kg of body weight of the blood by the same dose of several plasma-expanders, the injection of slowly aspirated own blood were repeated in every fifteen minutes, and the ratios were checked up to three hours.
Each expander was evaluated by the length of the time to keep those ratios in normal range. The saline and five per cent dextrose in water could keep those normal for only 30-60 minutes, but by using low molecular weight dextran, Haemacel, or Pan-amin D., the ratios remained within normal ranges up to 150 minutes.