日本輸血学会雑誌
Online ISSN : 1883-8383
Print ISSN : 0546-1448
ISSN-L : 0546-1448
CPD加濃縮血小板血漿の製造における最適遠心条件
大軒 子郎堂脇 義雄青木 裕紀子山口 英夫大久保 康人田中 正好
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1985 年 31 巻 3 号 p. 246-253

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Optimum centrifugation conditions for the preparation of platelet concentrate have been investigated from the aspects of quality and function of platelets including recovery, leukocyte contamination, pH, size distribution, aggregability, hypotonic shock response, shape change, adhesiveness and ATP release.
It was found that optimum results were obtained by centrifugation at the speed of 2, 000 rpm (1136×g) for five minutes in the preparation of platelet rich plasma, and at the speed of 3, 200rpm (1908×g) for five minutes in the preparation of platelet concentrate. The preparative protocols indicated greater effect on the quality of product in the first centrifugation of whole blood than in the second process.
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