抗Rh抗体による不適合輸血の一治験例

抄録

This is a report of a case which developed acute hemolytic reaction due to incompatible blood transfusion of anti-D and anti-C Rh antibody.
1) The case had received massive blood transfusion in the previous gastrectomy which, it is construed, probably gave rise to production of anti-Rh antibody and induced an antigen-antibody reaction in the concurrent blood transfusion. In order to prevent such complications it is advisable to test anti-D and anti-E antibody on those patients with histories of blood transfusion, stillbirth or abortion and if it is negative Coomb's test should be performed.
2) Shock due to incompatible blood transfusion under general anesthesia is evasive to detection, and so need of its careful detection cannot be over-emphasized.
3) As for the treatment plasma, plasma expander, massive administration of hydrocortisone and transfusion of Rh negative blood showed remarkable effects.