Abstract
A 14-year-old, neutered male Japanese Spitz presented with erythema, crust, and ulcer on the ventral abdomen and groin. Additional ulcers were noted on the mucous membrane of oral cavity, pinnae and ear canals. Complete blood counts and blood chemistry analyses did not show any abnormalities and antinuclear antibody was negative. Histopathologic findings showed liquefaction at the stratum basal with infiltration of mononuclear cells. Based on these findings, this dog was diagnosed as having vesicular cutaneous lupus erythematosus. To the best of our knowledge, this is the first report of an affected dog, which is not related with Shetland sheepdogs, Collies and these crosses.