Abstract
In canine demodicosis, it has been suggested that congenital or acquired disfunction of host immune system is associated with the onset or aggravation of the disease. In this report, we introduce a canine case of recurrent, refractory, and generalized form of juvenile-onset demodicosis whose skin lesions were improved after concomitant use of nigerooligosaccaride (NOS) supplementation, which was reported to have a potential to activate immune function in humans, with conventional therapy. Our finding suggests that NOS is available as an adjunct therapy for controlling systemic demodicosis in dogs, at least in certain cases.
