Abstract
A 3-month-old female Russian Blue received a second triple vaccine at 87 days of age. After 17 days, erosion and ulcer developed on the ear pinna, head, foot-pad and periungual, paronychia with a caseous exudate was also present. Histopathological examination showed subcorneal pustules containing acanthocytes. These findings were suggestive of pemphigus foliaceus. The eruption developed, and the cat was treated with prednisolone for 121 days. No recurrence has been observed for 2 years since the completion of treatment. Drug-induced pemphigus foliaceus due to the feline triple vaccine was suspected.