Abstract
We performed a retrospective evaluation of 29 cats with presumed idiosyncratic adverse cutaneous drug reactions (ACDR). ACDR accounted for 2% of the cats examined by the Dermatology Service over a period of 15 years. No breed, age, sex, or retroviral predilections were found. The most common cutaneous reaction patterns were contact dermatitis, contact otitis externa, allergy-like pruritus, and vasculitis. The most commonly incriminated drugs were amoxicillin clavulanate and chlorhexidine scrub. Drug withdrawal resulted in resolution of the skin eruptions within 2 to 6 weeks in 25 cats, and 12 weeks in 4 cats. Two cats with cefovecin-associated necrotizing vasculitis required additional anti-inflammatory therapy.
