2024 Volume 30 Issue 2 Pages 79-83
A 9-month-old intact female Bengal cat presented with a dry and scaly lesion limited to the nasal planum. After prednisolone administration, partial improvement of the nasal lesion was observed. However, the improvement was only temporary and lesion deterioration was observed again as the treatment continued. A skin scrape test showed only crusts. Wood’s light test and cultivation test showed no sign of fungal infection. Feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) were negative, and polymerase chain reaction (PCR) of the nasal swab ruled out bacterial and viral infection. A punch biopsy was performed on the nasal planum 3 weeks after prednisolone cessation. Histopathology revealed laminated orthokeratotic hyperkeratosis and very mild lymphocyte infiltration in the dermis layer. Topical application of difluprednate lotion led to gradual decrease of the lesion and a weekly application of this lotion is maintaining the status.