Abstract
Seven-year-old castrated mixed short-haired cat was presented with winter seasonal pinna alopecia. Autoagglutination test showed autohaemaglutination after refrigeration. Cryoprecipitation test of the serum and plasma showed precipitated materials after refrigeration, and these were dissolved after rewarming. The cat was diagnosed as having cryopathy associated with cold agglutinine, cryofibrinogen, and cryoglobulin. This cat was kept in warm room and treated with heparinoid agent unilaterally. Hair regrowth was observed on the treated pinna, and winter-seanonal pinna alopecia has been under control for 6 years.