Juntendo Medical Journal
Online ISSN : 2188-2126
Print ISSN : 2187-9737
ISSN-L : 2187-9737
Special Reviews: 343rd Triannual Meeting of the Juntendo Medical Society “Infectious Diseases Which Hide Close to You Unexpectedly”
Epidemiology of Severe Fever with Thrombocytopenia Syndrome in Japan
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2019 Volume 65 Issue 2 Pages 130-135


More than 17% of worldwide infectious diseases are caused by vector-borne diseases. A numerous number of living organisms can act as a vector. In Japan, tick-borne diseases are particularly important because these diseases occasionally lead to a fatal clinical outcome. Severe fever with thrombocytopenia syndrome (SFTS) is a newly identified tick-borne disease caused by phlebovirus in the Bunyaviridae family. Most SFTS patients have been observed in China, South Korea and Japan. SFTS was first identified in 2013 in Japan and reached to 310 cases by 2017 with a high case-fatality rate (7.8%). SFTS transmission cycles between ticks and wild animals have been already established throughout Japan. This review outlines the current epidemiology of SFTS in Japan, with an emphasis on ecology of vector and animals and clinical features of Japanese patients.

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© 2018 The Juntendo Medical Society. This is an open access article distributed under the terms of Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original source is properly credited.

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