順天堂醫事雑誌
Online ISSN : 2188-2126
Print ISSN : 2187-9737
ISSN-L : 2187-9737

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Clinical Significance of C-Reactive Protein in Patients with Trauma on Arrival
HIROKI NAGASAWA KAZUHIKO OMORIIKUTO TAKEUCHIKEI JITSUIKIHIROMICHI OHSAKAYOUICHI YANAGAWA
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ジャーナル オープンアクセス 早期公開

論文ID: JMJ19-OA10

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Objective: To investigate to investigate significance of C-reactive protein (CRP) in patients with trauma on arrival.

Materials: From September 2017 to February 2018, a medical chart review was retrospectively performed for all patients with trauma who were admitted to our department.

Methods: The subjects were divided into two groups: a CRP-negative group (initial CRP level ≤0.3 mg/dl) and a CRP-positive group (>0.3 mg/dl). For the CRP-positive group, we additionally investigated the cause of the increased level of CRP.

Results: There were 33 cases in the CRP-positive group and 168 in the CRP-negative group. The age and ratio of lymphocytes in the CRP-positive group was significantly higher than those in the CRP-negative group. Twenty-two to twenty-eight of the 33 cases (67-85%) had an infection, 3 of 33 (9%) had a delayed visit (over 24 h from the onset of the trauma) to the emergency department, and 2 cases (6%) had malignancy in the CRP-positive group. All subjects with an increased CRP level on arrival potentially had underlying diseases that might have caused their trauma.

Conclusion: Some traumatized patients may have elevated CRP levels on arrival due to underlying diseases capable of causing trauma. An increased initial level of CRP did not significantly affect the clinical outcome; however, physicians should pay attention to the cause of the increased CRP level, which may affect the patient’s outcome. Exploring increased CRP levels may be useful for identifying the mechanism underlying the occurrence of trauma.

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© 2018 The Juntendo Medical Society. This is an open access article distributed under the terms of Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original source is properly credited.

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