1999 Volume 66 Issue 1 Pages 41-44
Delayed-type hypersensitivity with granulomatous lesions to silk sutures is rather rate. Yet, braided silk sutures often act as a non-immunologic foreign-body and cause a granulomatous in-flammatory reaction years after surgery. We report here a case of recurrent granulomas with remarkable infiltration of eosinophils that may have resulted from an IgE-mediated hypersensitivity reaction to silk fibroin, a component of the braidid silk suture. Under normal circumstances exposure to fibroin is rather rare. Therefore, the present patient may have developed this reaction to the silk sutures used in a previous surgery. (J Nippon Med Sch 1999 ; 66 : 41-44)
