Journal of Nippon Medical School
Online ISSN : 1347-3409
Print ISSN : 1345-4676
ISSN-L : 1345-4676
Review
Recent Advances in Interventional Radiology for Acute Massive Pulmonary Thromboembolism
Hiroyuki TajimaSatoru MurataTatsuo KumazakiKen NakazawaKazuo IchikawaTsuyoshi YamamotoKeiji TanakaTeruo Takano
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2005 Volume 72 Issue 2 Pages 74-84

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Abstract
Acute massive pulmonary thromboembolism is life-threatening and requires vigorous treatment. Anticoagulation is the most traditional treatment for pulmonary thromboembolism, but may not be sufficient for massive thromboemboli. Systemic thrombolytic therapy and surgical thrombectomy are the traditional therapeutic options in this situation. Catheter-directed thrombolysis, percutaneous embolectomy and, more recently, percutaneous thrombus fragmentation techniques using specialized devices are now available to treat the most severe cases of massive pulmonary thromboembolism. The success of these techniques depends on a thorough understanding of the mechanism of action of each of the devices and familiarity with the relevant catheterization techniques. We present a review of currently available equipment and techniques, and describe our work with hybrid treatment using a combination of mechanical fragmentation, localized fibrinolysis and clot aspiration.
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© 2005 by the Medical Association of Nippon Medical School
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