非固定唾石とホルマリン固定液中に保存された唾石中のハイドロオキシアパタイトの比較検討

抄録

Eleven submandibular stones and 1 sublingual stone obtained from 12 cases of sialolithiasis were examined. The largest stone measured 1.7×0.8 cm. Nos 1-6 were unfixed and dried spontaneously after removal (unF) whereas Nos 7-12 were preserved in formalin fixative (FF).
All stones were subjected to infrared spectroscopic analysis (IR) and the examination with X-ray powdery diffraction method (X-D). In2 of 12 stones, the protein was the main component. In all stones other than these two, dry ashing (DA) was further carried out (800°C, 30 min. to 1 hour), followed by a reexamination with IR and X-D. In 2 stones, the amount of the ash available was insufficient for X-D analysis.
In 5 unF stones, IR and X-D findings prior to DA appeared to indicate HAp as the main component. After DA, however, 4 stones other than No. 6 had β-TCp as the main component, and only a very small amount of HAp was found.
In 3 FF stones, both IR and X-D examinations before and after DA revealed HAp as the main component, together with micro- to moderate amount of whitlockite before DA and β-TCp after DA.
Based on the above results, it was inferred that non-crystalline TCp (and/or pre-HAp and/or lower crystalline HAp) was detected as the main component of the stone when there was no water available sufficient enough to form a crystalline, whereas crystalline HAp was detected as the main component even after DA when the stones were stored in FF after removal because there was available water enough for ripening.