古典的条件付けにより大脳皮質聴覚野に生じる可塑的変化の光計測

抄録

Classical conditioning induced map plasticity in the adult sensory cortex has not been well investigated. In this study, we used voltage sensitive optical recording method to study map changes in the auditory cortex induced by fear conditioning with parining of sound and electric shock. From pair-conditioned group and pseudoconditioned group, the responses were recorded both before and after the conditioning. The result shows that after conditioning, only the response area to CS sound in the pair-condtioned group was increased. This suggests that many neurons in the auditory cortex exhibit a rapid tuning to the CS sound by the fear conditioning.