Comparison of Turnover of Thiamine Propyl Disulfide and Thiamine in Various Organs on Oral or Parenteral Administration to Rats

抄録

Turnover of thiamine in various organs was investigated by giving TPD-³⁵S (inner) or thiamine-³⁵S by mouth or by subcutaneous injection to white rats and the following results were obtained:
1. The turnover ratio of thiamine in the organs was increased day by day after daily oral administration or subcutaneous injection of TPD-³⁵S (inner) or thiamine-³⁵S.
2. The turnover ratio of thiamine in the organs was distinctly higher after administration of TPD-³⁵S (inner) by either route than in the case of thiamine-³⁵S.
3. No marked difference in the turnover ratio due to difference in the route of administration, oral or subcutaneous, of both TPD and thiamine was noted.