抄録
1. No biological activities of 2′, 3′-di-n-butyryl-4′, 5′-o-isopropyli-deneriboflavin and 4′, 5′-di-n-butyryl-2′, 3′-isopropylidene-riboflavin were observed.
2. Riboflavin-2′, 3′-di-n-butyrate and riboflavin-4′, 5′-di-n-butyrate showed the growth curves quite similar to free riboflavin, but markedly more active than riboflavin-tetra-n-butyrate.
3. Using vitamin B2-deficient rats, the curative experiments were performed, and the following results were obtained.
FR>B2-2′, 3′-di-n-butyrate>B2-4′, 5′-di-n-butyrate>B2-tetra-n-butyrate. The di-n-butyrates were more easily hydrolyzed in vivo than the tetra compound, and produce rbdoflavin.
