Abstract
1. The oxidation of Palmitate in rat liver intact mitochondria of the alcohol fed group was found to be lower than that of the control group. However, the oxidation of acetate in intact mitochondria of the alcohol fed group was found to be almost the same as that of the control group. As for the oxidation of palmitate in sonicated mitochondria, no difference was found between the alcohol fed group and control group.
2. The stimulatory effect of carnitine on the oxidation of both palmitate and acetate in intact mitochondria, and on the oxidation of palmitate in sonicated mitochondria were diminished in the alcohol fed group.
3. The administration of alcohol to rat was found to have some pathological effect on carnitine barrier site of mitochondrial membrane.
