Bioavailability and Biological Activity of L-Ascorbic Acid 2-O-α-Glucoside
1992 年 38 巻 Special 号 p. 161-164
詳細
1992 年 38 巻 Special 号 p. 161-164
AA-2G is a new stable derivative of AsA which is efficiently synthesized by regioselective transglucosylation with α-glucosidase and CGTase. AA-2G serves as a vitamin C supplement in experimental animals. AA-2G is easily hydrolyzed in vivo by α-glucosidase and also synthesized as a metabolite under some specified conditions. AA-2G stimulates collagen synthesis in cultured fibroblasts and enhances antibody production in cultured splenocytes. AA-2G which has no cytotoxicity is a promising AsA derivative for medical and nutritional uses.
