1992 年 38 巻 Special 号 p. 88-91
The third component of complement (C3) is a protein produced by osteoblastic cells in response to 1α, 25(OH)2D3. The bone C3 appears to be involved in differentiation of bone marrow cells into osteoclasts in concert with other vitamin D-dependent factors. Further studies are needed to understand the precise role of C3 in bone.