Effect of Exercise on the Metabolism of Vitamin B₆ and Some PLP-dependent Enzymes in Young Rats Fed a Restricted Vitamin B₆ Diet

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The effect of exercise on vitamin B₆ metabolism and PLP-dependent enzymes was studied in rats fed a diet with or without vitamin B₆. Metabolism of some amino acids (citrulline, arginine, ornithine and threonine) inhibited in the B₆-deficient rats was normal-ized during exercise. Exercise was also effective in storing vitamin B₆ in the body by lowering excretion of vitamin B₆, when intake of vitamin B₆ was restricted. Aspartatae aminotrans-ferase activity was higher in the red portion of the gastrocnemius muscle than that of the white one, whereas glycogen phosphorylase activity was vice versa and furthermore glyco-gen content in the white portion was very low in the vitamin B₆-deficient rat. From the data obtained, it has been suggested that the red and white portions of the gastrocnemius muscle seemed to be more important in metabolizing amino acids and hydrolyze glycogen, respec-tively.