Journal of Clinical Physiology
Online ISSN : 2435-1695
Print ISSN : 0286-7052
Original Article
Relationship between Serum N-terminal Pro-Brain Natriuretic Peptide Levels and Short-Term Mortality in Patients Hospitalized Nursing- and Healthcare-Associated Pneumonia
Yuji KAWASAKITomoya HARADAKenichi TAKEDAAkira YAMASAKI
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JOURNALS OPEN ACCESS

2019 Volume 49 Issue 5 Pages 169-173

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Abstract

 Background: The prognostic role of N-terminal probrain natriuretic peptide (NT-proBNP) in patients with nursing- and healthcare-associated pneumonia remains to be determined.

 Objective: The purpose of this study was to investigate the relationship between serum NT-proBNP levels and short-term mortality in patients hospitalized for nursing- and healthcare-associated pneumonia.

 Methods: Performance status, A-DROP severity score for pneumonia, serum albumin levels, and serum NT-proBNP levels in 14 patients who died within 30 days of admission (30-day mortality group) and 101 surviving patients (sur vivor group) hospitalized for nursing- and healthcare-associated pneumonia were compared.

 Results: Serum albumin levels were lower and serum NT-proBNP levels higher in the 30-day mortality group than in the survivor group. Since serum NT-proBNP is a biomarker for heart failure, higher levels in the 30- day mortality group suggest that short-term mortality in patients hospitalized for nursing- and healthcareassociated pneumonia is associated with heart failure.

 Conclusion: Serum NT-proBNP might offer a useful prognostic marker for short-term mortality in patients hospitalized for nursing- and healthcare-associated pneumonia.

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© 2019 Japanese Society of Clinical Physiology
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