Recent Advances in Medical Therapy for Heart Failure

抄録

　Heart failure (HF) is a chronic and progressive functional deterioration as a final common pathway of organic cardiac disorders. Its prevalence has been increasing worldwide, and to cope with this pandemic, various medical therapeutics including medical therapy has been developed. We herein review recently introduced four drugs for the treatment of HF (Sodium-glucose transporter 2 inhibitors, ivabradine, esaxerenone, and Angiotensin receptor-neprilysin inhibitor), especially focusing on the evidences from the population study and the presumed mechanisms involved.