エツクス線曝露時の白血球の貧喰能についての

抄録

To see the effects of radiant rays on the organism blood inspection method, including the calculation of numbers of red, white blood cells and lymphocytes and blood plates is in common use. But the radiant rays are assumed to affect the white blood cells themselves, therefore we have made an experiment on the phagocytes of white blood cells exporsed varying irradiation doses as a method to know their functional disturbances. Body weight and red and white blood cell counts were determined simultaneously with the observation of phagocytes. Three groups, each consisted of five matured male rabits, were irradiated with 50, 75 and 100r X ray respectively. Before irradiation and after that in one week interval blood of rabbits was taken by heart puncture. Carbon black suspension of given volume and concentration was added. And, for only neutrophile white blood cell, phagocytes rate was calculated. A group, consisted of five rabbits, was made as the control. Observations were extended over 6∼8 weeks. Experimental results: 1. The body weight: Any direct effects by irradiation were not observed. 2. Red blood cell counts: Tendency of decrease by irradiation was found, but statistically significant difference was found only between irradiation group of 50r. and the control. 3. White blood cell counts: Slight tendency of decrease by irradiation was seen, but statistically significant difference was not found between the irradiation groups and the control. 4. Rate of phagocytes: Every irradiation group showed marked decrease and statistically significant difference was found between the irradiation groups and the control. Decrease reached the maximum at the 2nd week after irradiation. Recovery period and the degree of decrease corresponded to the exposure dose. 5. As to the red and white blood cell counts fluctuations among animals of the control group were great durning the experiment, but fluctuations among animals of the irradiation groups were small and showed a consistent tendency. This may be, the environment in general on the organism.