抄録
We performed dynamic MRI with Gd-DTPA for evaluation of renal function.
As a basic study, we examined the relationship between the Gd-DTPA concentration and T1, T2 and T2* using a phantom and that between the flip angle and Gd-DTPA concentration using the gradient echo method. The pulse sequence (TR=70msec, TE=20msec, flip angle=70°) and the dose of Gd-DTPA 0.05mmol/kg were considered optimal. Dynamic MRI was performed in volunteers with a normal renal function and in patients with renal dysfunction. As a change of the time intensity curve in patients with disorders of the renal parenchyma, delay in signal decrease the aorta, decrease in peak signal intensity of the renal medulla, prolongation or disappearance of the cortico medullary junction time and delay in signal decrease of the renal parenchyma were observed. The signal in the renal pelvis was observed in some patients with renal parenchymal dysfunction. It was considered to represent a dysfunction of concentration.
Consequently, dynamic MRI was believed to be useful in evaluating the renal function.
