1958 年 70 巻 4 号 p. 1277-1285
It was previously reported by the members of the author's laboratory that the ascites of the guinea-pigs previously injected with chlorpromazine and then intraperitoneally inoculated with Rickettsia tsutsugamushi had a high degree of immune effect. In the present experiments, the distribution of the immunogenicity of the ascites was studied. The ascites was divided into 4 fractions, purified rickettsiae, cellular component and ascites serum, ascites albumin, ascites globulin and the rest components.
The immunogenicity was the highest in the fraction of purified rickettsiae, and the next in those of cellular component and ascites serum and of ascites albumin, whereas the fraction of ascites globulin showed no noticeable immune effect.