Experimental and clinical stadies on various gastric disease by histochemical staining with Coriphosphine O

(II) Clinical application to the diagnosis of early gastric cancer

Abstract

1. In six cases of early gastric cancer including the protruded type, superficial type and excavated type, findings of stomach X-ray, endoscopy and cytology as well as histopathological findings of biopsy specimens and the resected stomach were described in detail.
Particularly, the X-ray diagnosis, endoscopic diagnosis and their relationship to the macroscopic classification were discussed.
2. In the six cases of early gastric cancer, the histopathological pictures with hematoxylin-eosin staining were found to be in complete agreement with coriphorphine O (CO) staining characteristics. The CO fluorescence microscopic method was also shown to be a staining method capable of well representing the tissue structure.
Futher, the method is superior in the visualization of cells and is advantageous in the detection of atypical cell arrangement in early gastric cancer.