Abstract
The synthesis of formyl nitrocalix [4] arene derivatives each possessing two ester groups was carried out. Reaction of formyl nitrocalix [4] arene with ethyl bromoacetate in DMF gave only partial cone conformer, while reaction in acetone provided a mixture of partial cone and 1,3-alternate (38 and 52% yield, respectively). From the 1,3-alternate conformer, it showed be possible to obtain ionophore and precursor useful as new sensing agents.
