Abstract
It was previously confirmed that estragole, an essential oil obtained from Foeniculum vulgare Miller , has skin whitening effects. Furthermore, compounds synthesized from estragole have good tyrosinase inhibitory activity. We have therefore used estragole as a starting material to synthesize novel the compounds containing sulfur and oxygen that atoms. In tests of inhibitory activity against tyrosinase, these novel compounds showed higher skin whitening effects than the currently accepted skin whitening agents arbutin and kojic acid.
