Synthesis and Characterization of α-Bromo 5-Methyl Tetrazoles from Long Chain Fatty Alkenoates

Abstract

In view of synthetic utility and biological importance of tetrazole derivatives, 1′-phenylethyl undec-10-enoate, 1′-phenylethyl (Z)-octadec-9-enoate and 1′-phenylethyl (Z)-12-hydroxyoctadec-9-enoate have been converted into their α-bromo 5-methyl tetrazole derivatives, using bromine, acetonitrile and sodium azide as reagents. The structure elucidation of the prepared compounds is based on elemental analysis and spectral data.