Synthesis of Ribose - Oleic Acid Esters in the Presence- and Absence of Candida antarctica Lipase B

Abstract

D-ribose-oleic acid esters were produced with or without a biocatalyst, using in the same organic media, dimethyl sulfoxide (DMSO): tert-butanol (TBU) or 2-methyl-2-butanol (2M2B). The yield of the ester product was above 90% in both of the reactions. The biocatalyst used was lipase B of Candida antarctica. Molecular characterization was performed by using all the analytical methods available: IR, ¹H-NMR and ¹³C-NMR, HSQC, and ESI-MS.

graphical abstract