Abstract
Soysterol can be acetylated, brominated and then oxidized by using chromic anhydride ; water ; sulfuric acid; glacial acetic acid in carbon tetrachloride solution, and androstenolone is obtainable with stigmasetrol recovered. Yields of androstenolone and stigmasterol were investigated under various conditions. From 150 g of soysterol, iodine value 77.3 (pyridine bromide method), a 22 g of stigmasteryl acetate tetrabromide was recovered and 5.4 g of androstenolone acetate semicarbazone was obtained by using the oxidizing agent containing 228 g of chromic anhydride which was added during 7 hrs and then agitated for 15 hrs at 20°C.
The yield of androstenolone acetate semicarbazone was slightly increased by the addition of cupric sulfate as catalyst.
