Abstract
Various surfactants including linear alkylate sulfonate (LAS), alpha olefin sulfonate (AOS), sulfate of synthetic alcohol (AS), and a formulated detergent for kitchen use were applied on the clipped back skin of guinea-pigs, and after 24hr or 1week the histopathological reactions on those skin were observed.
The degrees of the reaction obtained were as follows : In 30% aqueous solutions of surfactants, AOS showed remarkably weaker reaction than LAS or AS, and the reactions of LAS and AS were approximately the same.
In 1% solutions of surfactants or in 10% solution of the detergent, every sample did not show any reactions on the test skins.
