Abstract
Dietary lipid is received by mucosal cells in the gastrointestinal tract before absorption from the small intestine, and the lipid enhances the secretion of various gut hormones, cholecystokinin, secretin, entroglucagon, PYY and glucose-dependent insulinotropic peptide, and stimulates enteric nervous system. Gut hormones and the nervous systems are interact each other and regulate gastrointestinal functions, exocrine secretion, gastric acid secretion, gastric emptying and mucosal growth of the small intestine. Also, properties of dietary fat, especially content of n-3 and n-6 fatty acids, influence colonic mucosal growth through production of icosanoids by mucosal cells. These are involved in inflammatory bowel disease and colon cancer.
