Journal of Japan Oil Chemists' Society
Online ISSN : 1884-1996
Print ISSN : 1341-8327
ISSN-L : 1341-8327
Synthesis of Hydrophilic Fluorosilane Coupling Oligomers Possessing Anti-Human Immunodeficiency Virus Type-1 Activity
Hideo SAWADAYuka IKEMATSUMasanori BABATokuzo KAWASEYoshio HAYAKAWA
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JOURNAL FREE ACCESS

1997 Volume 46 Issue 4 Pages 435-438,461

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Abstract
New fluoroalkyl end-capped oligomeric silane coupling agents were prepared by reactions of fluoroalkanoyl peroxides with trimethylvinylsilane, trimethoxyvinylsilane and acrylic acid. Fluoroalkylated co-oligomers thus obtained were found to be soluble not only in water but common organic solvents as well. The co-oligomers had a good hydrophilicity with a strong oleophobicity above the surface. They were also noted to possess a potent and selective anti-HIV-1 activity even under crosslinked conditions.
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