Journal of Oral Science
Online ISSN : 1880-4926
Print ISSN : 1343-4934
Original
Inhibitory activity of Aloe vera gel on some clinically isolated cariogenic and periodontopathic bacteria
Mohammadmehdi FaniJamshid Kohanteb
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Volume 54 (2012) Issue 1 Pages 15-21

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Abstract

Aloe vera is a medicinal plant with anti-inflammatory, antimicrobial, antidiabetic and immune-boosting properties. In the present study we investigated the inhibitory activities of Aloe vera gel on some cariogenic (Streptococcus mutans), periodontopathic (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis) and an opportunistic periodontopathogen (Bacteroides fragilis) isolated from patients with dental caries and periodontal diseases. Twenty isolates of each of these bacteria were investigated for their sensitivity to Aloe vera gel using the disk diffusion and microdilution methods. S. mutans was the species most sensitive to Aloe vera gel with a MIC of 12.5 μg/ml, while A. actinomycetemcomitans, P. gingivalis, and B. fragilis were less sensitive, with a MIC of 25-50 μg/ml (P < 0.01). Based on our present findings it is concluded that Aloe vera gel at optimum concentration could be used as an antiseptic for prevention of dental caries and periodontal diseases. (J Oral Sci 54, 15-21, 2012)

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© 2012 by Nihon University School of Dentistry
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