The Journal of Nihon University School of Dentistry
Online ISSN : 1884-2984
Print ISSN : 0029-0432
ISSN-L : 0029-0432
Biocompatibility of Tissue Conditioners
Histological Study in Rats
Luis Augusto PASSERIAntonio Cesar Perri de CARVALHO
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1985 年 27 巻 3 号 p. 167-173

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The purpose of this study was to verify histologically the biocompatibility of the tissue conditioners, F. I. T. T., Lynal, Visco-gel, and a zinc oxide and eugenol impression paste, when placed in intraoral wounds and surgical osseous cavities in rats. It was possible to conclude that the paste was the most irritating material. Among the tissue conditioners, Lynal and Visco-gel presented similar results and were more biocompatible.
The biocompatibility of tissue conditioners was verified histologically using 120 albino rats. The animals operated on in the palatal mucosa were sacrificed after 2, 5, 10, and 15 postoperative days, and those operated on in the mandible were sacrificed after 4, 8, 16, and 30 postoperative days. Based on histological sections, it was possible to conclude that zinc oxide and eugenol impression paste is the most irritating material to the tissues; the tissue conditioners presented varying degrees of biocompatibility and the best results were provided by “Lynal” and “Visco-gel.”

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