Journal of Pesticide Science
Online ISSN : 1349-0923
Print ISSN : 1348-589X
Original Article
Synthesis and biological activity of novel benzimidazole derivatives as potential antifungal agents
Weijie SiTao ZhangYaofa LiDongmei SheWenliang PanZhanlin GaoJun NingXiangdong Mei
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2015 Volume 41 Issue 1 Pages 15-19

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Abstract

In the present study, a series of novel benzimidazole derivatives containing chrysanthemum acid moieties was designed and synthesized. Preliminary investigation of biological activity indicated that all of the compounds exhibited lower activity than that of beta-cypermethrin against Plutella xylostella and Lipaphis erysimi; meanwhile, they showed good inhibitory activity against Botrytis cinerea and Sclerotinia sclerotiorum in vitro. The fungicidal activity of compound 8a against B. cinerea was approximately equal to that of thiabendazole and was twice as active against S. sclerotiorum as was thiabendazole. In addition, compound 9e displayed the most potent inhibitory activity against both fungi and was almost twice as potent as thiabendazole.

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© 2016 Pesticide Science Society of Japan
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