Indoor behavior prediction and risk assessment of an active substance in an aerosol for controlling flies and mosquitoes under various conditions

Abstract

Using the fugacity model InPestCFD, we predicted the indoor behavior of an active substance in an aerosol intended for controlling flies and mosquitoes under various conditions and conducted a comprehensive risk assessment. In predicting behavior, we examined the impact of spraying methods, room air exchange rates, position of an air inlet, and location of a bed, revealing spatiotemporal behaviors not observed previously. For the risk assessment, we predicted the exposure levels for adults and children based on different scenarios from the predicted concentrations and compared them with the acceptable levels of the active substance. Comparison of the obtained results with the results of risk assessment currently conducted in Japan and the United States revealed that current guidelines are considerably conservative in the United States and sufficiently conservative in Japan.