Synthesis and Acaricidal Activity of Bicyclic Pyrazole-3-carboxamide Derivatives

Abstract

Twenty-six bicyclic pyrazole derivatives were synthesized and their acaricidal activity was studied. Among them, N-(4-tert-butylbenzyl)-2, 6-dimethyl-2, 4, 5, 6-tetrahydrocyclo-pentapyrazole-3-carboxamide (21) was the most effective and a promising acaricide, whose activity against both Tetranychus urticae and Panonychus citri was almost equal to that of MK-239 (tebufenpyrad).