Abstract
Fungicidal activities of N-(substituted-aryl)-2-chloropyridine-3-carboxamides against grey mold (Botrytis cinerea) and rice sheath blight (Rhizoctonia solani) were analyzed quantitatively by using their physicochemical and structural parameters and the multiple regression technique. The results clearly indicated that alkyl substituents at a position ortho to the amino group (Iso) and molecular hydrophobicity (logk′) were important factors in determining antifungal activity against grey mold. With respect to activity against rice sheath blight, the studies demonstrated that the presence of alkyl groups at meta-position (Ism) along with molecular size (IR5 and VW) were significantly influential towards antifungal activity.
