Molecular Cloning of Monkey Histamine H₄ Receptor

抄録

Histamine H₄ receptor is considered as a novel therapeutic target for allergic diseases. To enhance the knowledge about species difference, which is essential for drug discovery research, monkey H₄ receptor was identified. Monkey H₄ receptor was characterized to have comparable similarity with its human counterpart. Discovery of monkey H₄ receptor will contribute to a better interpretation of effective drug discovery.