The Japanese Journal of Pharmacology
Online ISSN : 1347-3506
Print ISSN : 0021-5198
ISSN-L : 0021-5198
Gastric Lesion-Preventing or -Potentiating Activity of Clonidine in Rats
Piero DEL SOLDATO
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1986 年 41 巻 2 号 p. 257-259

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抄録
The dual effects of clonidine on gastric experimental damage have been studied in the rat. At lower doses, clonidine prevents gastric lesions induced by oxotremorine plus neostigmine, probably through an α2-agonist mechanism; at higher doses, the compound potentiates dimaprit-induced gastric damage, probably through an H2-agonist mechanism.
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© The Japanese PharmacologicalSociety
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