Synthesis of 2-Oxazolidinone from β-Aminoalcohol Using Supercritical Carbon dioxide

Hajime Kawanami; Yutaka Ikushima

doi:10.1627/jpi.45.321

Hajime Kawanami, Yutaka Ikushima

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Keywords: 2-Oxazolidinone, Amino alcohol, Carbon dioxide, Supercritical condition, Chemical fixation

JOURNAL FREE ACCESS

2002 Volume 45 Issue 5 Pages 321-324

DOI https://doi.org/10.1627/jpi.45.321

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Abstract

The synthesis of 2-oxazolidinone from β-amino alcohol by chemical fixation of carbon dioxide under supercritical conditions using N, N'-dicyclohexylcarbodiimide (DCC) was developed. Even though in non-solvent conditions, 2-oxazolidinone was synthesized with a maximum yield of 96.7% at the critical pressure.

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