尿道ノ白斑(ロイコブラキー)ニ就テ

抄録

The first case, a man 27 years old, clerk, strong, healthy and in good constitution. He has never been suffering from any serious diseases. Since 6 years he was infected by gonorrhoea and is still under medical treatment today. In its course 4 years ago, he took notice of a spot on the surface of fossa navicularis, which grew gradually, day after day, in its peripheric, and lately it is becoming more or less painful during urination election and cohabitation and after bodily struggle. Strenuous antiluetis cure took no effect. For 4 years, for the purpose of treatment of chronic urethritis, instillation of concentrated solution of caustic silver and introduction of Bougie were continuously repeated many times. The above mentioned spot situated in fossa navicularis reached now 1.5cm. long and 0.9cm. breadth and coloured grey or silver white and glittererd as cholesteatom aud shatply circumscribed from the neighbouring urethral membrance. The central part of this spot is as hard as cartilage, and it is softer and larger at a distance from the center peripheralwards and at last the extreme part is only a little harder than the urethral membrance. Its surface is smooth and full of falds and somewhat eminated on surface of urethral menbrance. The lowest part of this spot is embeded in the urethral membrance and rather indurated, so the spot is palpable with fingers from the outside as a tumor on the whole. It does not show any tendency to spontaneous healing and all subjective and objective symptomes lately grew more and more extensive, so was radicaliy extirpated. Operative and postoperative troubles were never brought to light. On the pathologic histologic studies of this extirpated materials (1) a highest state of hyperkeratosis (2) and parakerotosis (3) luxuriantly growing and branching of the papille (4) dilated capillary (5) cell-infiltration etc. were remarkable.
The second case. a man of 32, a workman. Nothing to denote here in his family and previous history, especially was never infected by lues. 10 years before he was infected by gonorrhoea, which almost cured by medical remedy, only lefting the light stricture of regio orificium urethrae externa, and then medically treated as in the first case, according to his statement. In october last he was reinfected by gonorrhoea, once in the course of its treatment became periurethoral abscess, then incision. By inspection from orificium and by palpation from the outside, following facts (1) there is a spot on the membrance of fossa navicularis which is spreading as a fancy towards orificium. (2) the spot reached 1cm. long and 0.8cm breadth were seen. Not only the clinical subjective symptonies and objectve appearances but pathologic-histologic studies of extirpated materials were fairly consistent with what could be experienced in the first case above mentioned.
Comparing all the facts which could be obtained by the clinical and pathologic-histologis studies of the 2 cases of Leucoplakia of fossa navicularis with which reported by Dorsdress O. and English J. and Borza T. and other authorities on the problem of Leucoplakia of urogenital tract. I can conclude that, (1) both middle aged, (2) man, (3) the leucoplakia of the first case stand on fossa navicularis, that of the second stand on fossa navicularis and its neighbourhood, (4) took long process. (5) in the beginning progressed favourably, but lately turned to be more or less serious subjective troubles, (6) at all circumscribed, (7) as its source we can absolutely neglect lues and support (A) acute gonorrhoea which turned out chronic form, (B) continuously and repeatedly happened a great many number of times irritations on urethral membrance caused by chemical (caustic silver solution) and mechanical (Bougie treatment, (8) never showed spontaneous healing, (9) so might be surgically extirpated, (10) on pathologic-histologic studies, I saw the facts above mentioned in the first case, which certifies its diagnosis as Leuco