STUDIES OF CLEARANCE TESTS IN UROLOGY

Abstract

I. Clinical Studies
I have compared the following 4 kinds of clearance test (GFR, RPF, RBF, FF) with phenolsul-fonphthalein, Fishberg's concentration, blood creatinine, indigo-carmine tests and excretory urography in several kinds of urological disease.
The conclusions are the following:
1. Endogenous creatinine clearance can be able to apply as GFR.
2. I have studied on renal function in urological diseases, as follows: renal tuberculosis, renal calculus, prostate hypertrophy and the other miscellaneous diseases. I have confirmed that these clearance tests are one of a sensitive renal function tests.
3. I have observed that a high-power correlation existed between GFR, RPF, RBF and phenolsulfonphthalein test, concentration test, blood creatinine.
4. According to the degree of renal lesion, the quantity of phenolsulfonphthalein during one hour and GFR, RPF, RBF showed the parallel results.
5. I have studied the postoperative renal function in five cases of renal tuberculosis and in two cases of prostate hypertrophy.
II. Experimental Studies
I have observed prae-and postoperative renal function of unilateral nephrectomy, unilateral and bilateral partial nephrectomy, and renal-bisection with rabbits. Renal function has recovered in three or four weeks in unilateral operative cases. In the rest of kidneys or in bilateral cases the postoperative prognosis has been most discouraging. I have confirmed these clearance tests have been one of a sensitive renal function tests also in experimental studies.